Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 9/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 8/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.31 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | RET | P07949 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | LTK | P29376 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31542230 | 0.97 | CRBN (0.33) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542250 | 0.97 | DDB1 (0.32) | CRBNDDB1CHRM4ALKCYP3A4 | |
| SCHEMBL31542200 | 0.95 | MEN1 (0.35) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542236 | 0.95 | CHRM4 (0.33) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542240 | 0.95 | DDB1 (0.34) | CRBNDDB1IKZF2ALKEGFR | |
| SCHEMBL31542195 | 0.95 | CRBN (0.36) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542231 | 0.94 | IKZF2 (0.31) | CRBNDDB1IKZF2ALKEGFR | |
| SCHEMBL31542182 | 0.94 | CRBN (0.35) | CRBNDDB1IKZF2ALKEGFR | |
| SCHEMBL31542227 | 0.94 | ALK (0.31) | CRBNDDB1ADRA1DADRA1AADRA1B | |
| SCHEMBL31542201 | 0.94 | DDB1 (0.33) | CRBNDDB1IKZF2ALKEGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025062330-A1 | HETEROCYCLIC COMPOUNDS AS CBP SELECTIVE DEGRADERS | AURIGENE ONCOLOGY LIMITED (IN) | 2025-03-27 | — | — | WO | disclosed |