SCHEMBL31542614

SCHEMBL31542614

COc1c2occc2c(O)c2ccc(=O)oc12

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 8/20 0.80
KDM4E B2RXH2 6/20 0.80
CYP1A2 P05177 5/20 0.80
CYP1A1 P04798 4/20 0.80
CYP1B1 Q16678 4/20 0.80
HPGD P15428 4/20 0.80
POLB P06746 1/20 0.80
ALDH1A1 P00352 7/20 0.68
ALOX15 P16050 1/20 0.68
MAPT P10636 3/20 0.60
ABCB1 P08183 1/20 0.60
KCNA2 P16389 2/20 0.57
CYP2A6 P11509 3/20 0.56
CYP2D6 P10635 3/20 0.56
CYP2C19 P33261 3/20 0.56
MAOA P21397 3/20 0.56
TSHR P16473 2/20 0.56
PDE4A P27815 2/20 0.56
MAPK1 P28482 2/20 0.56
ACHE P22303 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434686 1.00 CYP3A4 (0.80) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
Isopimpinellin SCHEMBL29568822 0.89 CYP3A4 (1.00) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
Isopimpinellin SCHEMBL498907 0.89 CYP3A4 (1.00) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL4187228 0.85 CYP3A4 (0.80) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL20278781 0.85 CYP3A4 (0.80) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL6361059 0.85 CYP3A4 (0.75) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
Pimpinellin SCHEMBL2255899 0.81 CYP3A4 (1.00) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL5960652 0.81 CYP3A4 (0.74) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL6200404 0.81 CYP3A4 (0.74) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1
SCHEMBL2383938 0.81 CYP3A4 (0.74) CYP3A4KDM4ECYP1A2CYP1A1CYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119752833-A Oxygen methyl transferase and application thereof in biocatalysis synthesis of O-methylated product 湖北碳元本草生物科技有限公司 2025-04-04 CN claimed
CN-119752833-A Oxygen methyl transferase and application thereof in biocatalysis synthesis of O-methylated product 湖北碳元本草生物科技有限公司 2025-04-04 CN disclosed
CN-119752833-A Oxygen methyl transferase and application thereof in biocatalysis synthesis of O-methylated product 湖北碳元本草生物科技有限公司 2025-04-04 CN disclosed