SCHEMBL31546372

SCHEMBL31546372

CCCN1CCC(CNC(=O)C2CCN(c3nc(-c4ccc(OC)cc4)no3)CC2)C1

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.64
▸ KMT2A Q03164 4/20 0.64
▸ LMNA P02545 2/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.58
▸ MAPT P10636 2/20 0.55
▸ POLB P06746 1/20 0.53
▸ NPC1 O15118 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ HSP90AA1 P07900 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31546394 0.93 MEN1 (0.64) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL31546456 0.92 MEN1 (0.63) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL30584702 0.91 MEN1 (0.63) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL25433029 0.91 MEN1 (0.67) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL25433025 0.91 MEN1 (0.67) MEN1KMT2ALMNASMN1; SMN2MAPT
Formic Acid SCHEMBL31546404 0.90 MEN1 (0.61) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL25399675 0.90 MEN1 (0.63) MEN1KMT2ALMNASMN1; SMN2MAPT
Formic Acid SCHEMBL31546424 0.90 MEN1 (0.60) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL31546328 0.90 MEN1 (0.63) MEN1KMT2ALMNASMN1; SMN2MAPT
SCHEMBL31546327 0.90 MEN1 (0.63) MEN1KMT2ALMNASMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer ANIMA BIOTECH INC. (US) 2025-07-01 — — US disclosed
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER ANIMA BIOTECH INC. (US) 2025-04-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12344600-B2 c-Myc mRNA translation modulators and uses thereof in the treatment of cancer MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885
US-20250109128-A1 C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER MYC, MYCBP, MYCBP2 MEN1 1569/4885KMT2A 1404/4885LMNA 1344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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