Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 14/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | FAP | Q12884 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2098557 | 0.86 | MAPT (0.51) | DPP4FAPTP53 | |
| Hydrochloric Acid SCHEMBL2098558 | 0.86 | MAPT (0.51) | DPP4FAPTP53 | |
| SCHEMBL2101388 | 0.75 | MAPT (0.49) | CHRM1CYP2D6HRH1TP53 | |
| SCHEMBL22465037 | 0.75 | HRH1 (0.64) | DPP4CYP3A4KCNH2CHRM1CYP2D6 | |
| SCHEMBL22465422 | 0.75 | HRH1 (0.64) | DPP4CYP3A4KCNH2CHRM1CYP2D6 | |
| SCHEMBL22465035 | 0.75 | HRH1 (0.64) | DPP4CYP3A4KCNH2CHRM1CYP2D6 | |
| SCHEMBL2098253 | 0.74 | MAPT (0.47) | DPP4TP53 | |
| SCHEMBL3150575 | 0.74 | DPP4 (0.49) | DPP4KCNH2CHRM1CYP2D6HRH1 | |
| SCHEMBL20920005 | 0.74 | DPP4 (0.60) | DPP4CYP3A4SOS1KCNH2TRPC6 | |
| SCHEMBL20920007 | 0.74 | DPP4 (0.60) | DPP4CYP3A4SOS1KCNH2TRPC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863790-B1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI AVENTIS (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-1863790-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | Sanofi-Aventis (FR) | 2007-12-12 | — | — | EP | disclosed |
| WO-2006099943-A1 | AMIDE-SUBSTITUTED 8-N-BENZIMIDAZOLES, METHOD FOR THE PRODUCTION THEREOF, AND USE OF THE SAME AS MEDICAMENTS | SANOFI-AVENTIS (DE) | 2006-09-28 | — | — | WO | disclosed |