Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.48 |
| ▸ | KDM1A | O60341 | 3/20 | 0.48 |
| ▸ | GAK | O14976 | 2/20 | 0.48 |
| ▸ | ILK | Q13418 | 2/20 | 0.48 |
| ▸ | PLK4 | O00444 | 1/20 | 0.48 |
| ▸ | CIT | O14578 | 1/20 | 0.48 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | EPHB6 | O15197 | 1/20 | 0.48 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.48 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.48 |
| ▸ | BUB1 | O43683 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.48 |
| ▸ | STK10 | O94804 | 1/20 | 0.48 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.48 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1979453 | 0.79 | EGFR (0.52) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL29493193 | 0.79 | EGFR (0.52) | EGFRERBB2KDM1AGAKILK | |
| Hydrochloric Acid SCHEMBL30963337 | 0.78 | EGFR (0.52) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL14811309 | 0.77 | EGFR (0.55) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL7858883 | 0.74 | EGFR (0.49) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL16212567 | 0.73 | EGFR (0.46) | EGFRERBB2KDM1AGAKILK | |
| Hydrochloric Acid SCHEMBL1436789 | 0.72 | EGFR (0.52) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL2841492 | 0.71 | EGFR (0.68) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL2841494 | 0.68 | EGFR (0.66) | EGFRERBB2KDM1AGAKILK | |
| SCHEMBL14482031 | 0.67 | EGFR (0.73) | EGFRERBB2KDM1AGAKILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2162444-A2 | AN IMPROVED PROCESS FOR ERLOTINIB HYDROCHLORIDE | Hetero Drugs Limited (IN) | 2010-03-17 | — | — | EP | claimed |
| WO-2009007984-A2 | AN IMPROVED PROCESS FOR ERLOTINIB HYDROCHLORIDE | HETERO DRUGS LIMITED (IN) | 2009-01-15 | — | — | WO | claimed |