Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28957694 | 0.85 | NPC1 (0.49) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL30273459 | 0.84 | NPC1 (0.48) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL28957738 | 0.84 | NPC1 (0.48) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL31549995 | 0.79 | NPC1 (0.43) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL21588829 | 0.78 | NPC1 (0.41) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL30273545 | 0.78 | NPC1 (0.41) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL31632647 | 0.77 | NPC1 (0.53) | NPC1RAB9APKMKMT2ACYP11B2 | |
| SCHEMBL22997125 | 0.76 | NPC1 (0.61) | NPC1RAB9APKMKMT2AGRM1 | |
| SCHEMBL28360818 | 0.76 | KMT2A (0.59) | NPC1RAB9APKMKMT2ACYP11B2 | |
| SCHEMBL21588932 | 0.76 | NPC1 (0.40) | NPC1RAB9APKMKMT2AGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954709-A | Preparation method of sulfoxide compound, aniline compound and preparation method of aniline compound | 帕潘纳(北京)科技有限公司 | 2025-05-09 | — | — | CN | disclosed |