Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | IGF1R | P08069 | 1/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31553409 | 0.95 | ESR2 (0.67) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL31553363 | 0.95 | ESR2 (0.67) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL30090221 | 0.90 | HDAC1 (0.55) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL24038851 | 0.90 | HDAC1 (0.55) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL25110311 | 0.89 | NR1H2 (0.67) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL5077823 | 0.89 | NR1H2 (0.61) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL9257641 | 0.88 | NR1H2 (0.73) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL29589913 | 0.86 | NR1H2 (0.67) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL2277894 | 0.86 | NR1H2 (0.67) | NR1H2ESR2HDAC6HDAC8HDAC1 | |
| SCHEMBL29373737 | 0.86 | NR1H2 (0.70) | NR1H2ESR2HDAC6HDAC8HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119816495-A | 1,3, 4-Oxadiazole derivative compounds as histone deacetylase 6 inhibitors and uses thereof | 株式会社钟根堂 | 2025-04-11 | — | — | CN | disclosed |