Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | HSPB1 | P04792 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.30 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31554581 | 1.00 | S1PR4 (0.39) | S1PR4HSPB1MAPTSMN1; SMN2POLB | |
| SCHEMBL4250279 | 0.86 | S1PR4 (0.40) | S1PR4HSPB1MAPTSMN1; SMN2POLB | |
| SCHEMBL31554477 | 0.84 | AXL (0.33) | — | |
| SCHEMBL20587908 | 0.82 | S1PR4 (0.32) | S1PR4 | |
| SCHEMBL29822015 | 0.82 | S1PR4 (0.32) | S1PR4 | |
| SCHEMBL31236698 | 0.78 | S1PR4 (0.40) | S1PR4HSPB1MAPTSMN1; SMN2POLB | |
| SCHEMBL2881855 | 0.77 | S1PR4 (0.35) | S1PR4MAPTSMN1; SMN2RAB9AALDH1A1 | |
| SCHEMBL2882599 | 0.76 | CYP19A1 (0.33) | S1PR4 | |
| SCHEMBL20589057 | 0.76 | CYP1A2 (0.44) | S1PR4POLBALDH1A1MAPK1MEN1 | |
| SCHEMBL20588180 | 0.74 | ALOX5AP (0.30) | S1PR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096463-A1 | PLK4 MODULATORS | VIBLIOME THERAPEUTICS, LLC (US) | 2025-05-08 | — | — | WO | disclosed |