SCHEMBL31554601

SCHEMBL31554601

CNC(=O)COc1cc2cc(Nc3nc(N4CCN(c5ccc6c(c5)CN(C5CCC(=O)NC5=O)C6=O)CC4)ncc3Cl)ccc2n(C)c1=O

nearest known ligand 0.62

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 9/20 0.62
▸ NCOR2 Q9Y618 4/20 0.62
▸ MELK Q14680 1/20 0.59
▸ CHRM4 P08173 1/20 0.48
▸ BCL6B Q8N143 1/20 0.48
▸ PTK2 Q05397 4/20 0.45
▸ ESR1 P03372 3/20 0.43
▸ CRBN Q96SW2 3/20 0.42
▸ GSPT1 P15170 1/20 0.42
▸ DDB1 Q16531 1/20 0.42
▸ IKZF3 Q9UKT9 1/20 0.42
▸ ALK Q9UM73 1/20 0.41
▸ IKZF2 Q9UKS7 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31554667 1.00 BCL6 (0.62) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL31554602 1.00 BCL6 (0.62) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL31595248 0.97 BCL6 (0.58) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL23267914 0.97 BCL6 (0.58) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL23267882 0.95 BCL6 (0.56) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL24718120 0.95 BCL6 (0.56) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL30894272 0.95 BCL6 (0.56) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL31595353 0.95 BCL6 (0.56) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL23266445 0.94 BCL6 (0.55) BCL6NCOR2MELKCHRM4BCL6B
SCHEMBL31595453 0.94 BCL6 (0.55) BCL6NCOR2MELKCHRM4BCL6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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