SCHEMBL31554606

SCHEMBL31554606

O=C1CCC(N2C(=O)c3ccccc3C2Br)C(=O)N1

nearest known ligand 0.61

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 19/20 0.61
▸ DDB1 Q16531 14/20 0.61
▸ IKZF3 Q9UKT9 3/20 0.61
▸ ALDH1A1 P00352 1/20 0.61
▸ CHRM2 P08172 1/20 0.61
▸ OPRM1 P35372 1/20 0.61
▸ CYP1A2 P05177 1/20 0.61
▸ TSHR P16473 1/20 0.61
▸ TDP1 Q9NUW8 1/20 0.61
▸ TNF P01375 2/20 0.54
▸ IL1B P01584 2/20 0.54
▸ IKZF1 Q13422 2/20 0.54
▸ TBXA2R P21731 1/20 0.54
▸ BRD4 O60885 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23226068 0.85 CRBN (0.62) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL4163462 0.84 CRBN (0.61) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL19771065 0.84 CRBN (0.61) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL24762106 0.84 CRBN (0.61) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL20153862 0.84 CRBN (0.61) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL22564890 0.83 CRBN (0.59) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL23565388 0.83 CRBN (0.59) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL23534054 0.81 CRBN (0.57) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL22006260 0.81 CRBN (0.57) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL23534460 0.81 CRBN (0.57) CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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