SCHEMBL31554638

SCHEMBL31554638

CNC(=O)COc1cc2cc(Nc3nc(N4CCC(CN)CC4)ncc3Cl)ccc2n(C)c1=O

nearest known ligand 0.75

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 0.75
▸ MELK Q14680 1/20 0.75
▸ NCOR2 Q9Y618 5/20 0.74
▸ CHRM4 P08173 1/20 0.60
▸ BCL6B Q8N143 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23267253 0.93 BCL6 (0.76) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284725 0.92 BCL6 (0.79) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284547 0.92 BCL6 (0.74) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284198 0.92 BCL6 (0.78) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL22932328 0.92 BCL6 (0.78) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284724 0.92 BCL6 (0.83) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267254 0.91 BCL6 (0.77) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23250119 0.91 BCL6 (0.72) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL29873896 0.91 BCL6 (0.72) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267508 0.90 BCL6 (0.76) BCL6MELKNCOR2CHRM4BCL6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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