SCHEMBL31554754

SCHEMBL31554754

Cn1c(=O)c(OCC(N)=O)cc2cc(Nc3nc(N4CCC(C(=O)O)CC4)ncc3Cl)ccc21

nearest known ligand 0.65

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ BCL6 P41182 20/20 0.65
▸ MELK Q14680 1/20 0.65
▸ NCOR2 Q9Y618 6/20 0.64
▸ CHRM4 P08173 1/20 0.56
▸ BCL6B Q8N143 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20284526 0.94 BCL6 (0.66) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284233 0.92 BCL6 (0.76) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284386 0.87 BCL6 (0.72) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284569 0.87 BCL6 (0.68) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284725 0.87 BCL6 (0.79) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284079 0.87 BCL6 (0.69) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267911 0.86 BCL6 (0.59) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL20284393 0.86 BCL6 (0.64) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267427 0.85 BCL6 (0.72) BCL6MELKNCOR2CHRM4BCL6B
SCHEMBL23267434 0.85 BCL6 (0.67) BCL6MELKNCOR2CHRM4BCL6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025096706-A1 MODULATORS OF BCL6 AS LIGAND DIRECTED DEGRADERS BRISTOL-MYERS SQUIBB COMPANY (US) 2025-05-08 — — WO disclosed
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