Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | PKN1 | Q16512 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31556445 | 1.00 | MAOB (0.47) | MAOBCYP2C9CYP2C19ATMKMT2A | |
| SCHEMBL2671386 | 0.84 | PIK3C3 (0.47) | ATMKMT2AKDM4EALDH1A1NPC1 | |
| SCHEMBL31194372 | 0.83 | BRD4 (0.43) | MAOBATMKMT2AKDM4EALDH1A1 | |
| SCHEMBL13387026 | 0.81 | TDP1 (0.51) | KMT2AKDM4EALDH1A1HPGDNPC1 | |
| SCHEMBL4410049 | 0.81 | PIK3C3 (0.44) | KDM4EALDH1A1HPGDRAB9APOLB | |
| SCHEMBL28869904 | 0.81 | PKN1 (0.50) | MAOBCYP2C9CYP2C19ATMKMT2A | |
| SCHEMBL12709594 | 0.79 | PIK3C3 (0.50) | KMT2AKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL31194336 | 0.79 | PIK3C3 (0.50) | KMT2AKDM4EALDH1A1HPGDMAOA | |
| SCHEMBL1965011 | 0.78 | KMT2A (0.65) | ATMKMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL30447626 | 0.78 | KMT2A (0.65) | ATMKMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025068354-A1 | SMARCA2 INHIBITORS USEFUL FOR THE TREATMENT OF SMARCA4 DEFICIENT CANCERS | JANSSEN PHARMACEUTICA NV (BE) | 2025-04-03 | — | — | WO | disclosed |