Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WEE1 | P30291 | 16/20 | 0.57 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506461 | 1.00 | WEE1 (0.57) | WEE1ALKEGFRAXL | |
| SCHEMBL21373408 | 1.00 | WEE1 (0.57) | WEE1ALKEGFRAXL | |
| SCHEMBL21373346 | 0.92 | WEE1 (0.65) | WEE1ALK | |
| SCHEMBL29506474 | 0.92 | WEE1 (0.65) | WEE1ALK | |
| SCHEMBL21373276 | 0.89 | WEE1 (0.59) | WEE1 | |
| SCHEMBL21373363 | 0.89 | WEE1 (0.61) | WEE1 | |
| SCHEMBL29506442 | 0.89 | WEE1 (0.61) | WEE1 | |
| SCHEMBL29506465 | 0.89 | WEE1 (0.59) | WEE1 | |
| SCHEMBL31557303 | 0.87 | WEE1 (0.75) | WEE1AXL | |
| SCHEMBL21373343 | 0.87 | WEE1 (0.75) | WEE1AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025074275-A1 | COMBINATION THERAPIES INCLUDING MYT1 INHIBITORS AND WEE1 INHIBITORS | REPARE THERAPEUTICS, INC. (CA) | 2025-04-10 | — | — | WO | disclosed |