SCHEMBL31560079

SCHEMBL31560079

COc1cc(Cn2cccn2)cc2onc(-c3c(N4CCNCC4)cccc3S(N)(=O)=O)c12

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ KAT7 O95251 20/20 0.52
▸ KAT6A Q92794 20/20 0.52
▸ KAT6B Q8WYB5 11/20 0.52
▸ KAT5 Q92993 11/20 0.52
▸ KAT8 Q9H7Z6 11/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31560067 0.93 KAT7 (0.48) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560088 0.91 KAT7 (0.51) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560084 0.89 KAT7 (0.50) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560073 0.88 KAT7 (0.50) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560100 0.86 KAT7 (0.48) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560074 0.84 KAT7 (0.52) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560099 0.76 KAT7 (0.48) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560086 0.76 KAT7 (0.55) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL31560083 0.75 KAT6A (0.46) KAT7KAT6AKAT6BKAT5KAT8
SCHEMBL30680822 0.75 KAT7 (0.74) KAT7KAT6AKAT6BKAT5KAT8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119836416-A KAT6 targeting compounds with ubiquitin ligase binding moiety 普莱鲁德疗法有限公司 2025-04-15 — — CN disclosed
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