Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.96 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | GFER | P55789 | 1/20 | 0.62 |
| ▸ | YWHAG | P61981 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | CDC7 | O00311 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3654065 | 1.00 | NPC1 (0.96) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL3083169 | 0.98 | NPC1 (1.00) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL605593 | 0.98 | NPC1 (1.00) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL17009548 | 0.96 | NPC1 (0.89) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| Trifluoroacetic Acid SCHEMBL5104669 | 0.87 | NPC1 (0.79) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL3961543 | 0.86 | NPC1 (0.72) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL7102897 | 0.86 | NPC1 (0.73) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL7101608 | 0.84 | NPC1 (0.76) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL28086833 | 0.84 | NPC1 (0.70) | NPC1KDM4EMAPTHSD17B10MEN1 | |
| SCHEMBL325422 | 0.84 | NPC1 (0.70) | NPC1KDM4EMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025078808-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2025-04-17 | — | — | WO | disclosed |