Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 5/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20521260 | 1.00 | USP30 (0.50) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL31566998 | 1.00 | USP30 (0.50) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL31567024 | 0.91 | USP30 (0.48) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL31566861 | 0.91 | USP30 (0.48) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL31171576 | 0.91 | USP30 (0.48) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL5895323 | 0.91 | USP2 (0.47) | USP30USP2SMN1; SMN2CRBNDDB1 | |
| SCHEMBL31171500 | 0.90 | USP30 (0.47) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL2158895 | 0.89 | USP30 (0.46) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL20601939 | 0.89 | USP30 (0.42) | USP30CYP11B2USP2SMN1; SMN2ACACB | |
| SCHEMBL4985158 | 0.87 | USP30 (0.44) | USP30CYP11B2USP2SMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |