Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29215662 | 0.91 | USP2 (0.49) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL31231171 | 0.91 | USP2 (0.49) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL396843 | 0.85 | EPHX1 (0.49) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL4609802 | 0.84 | EPHX1 (0.51) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL25271054 | 0.82 | HPGD (0.44) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL30342339 | 0.82 | NR1H2 (0.39) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL20415351 | 0.82 | NR1H2 (0.39) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL19410867 | 0.82 | HPGD (0.50) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL31170608 | 0.81 | HPGD (0.47) | HPGDUSP2SMN1; SMN2GPR119RECQL | |
| SCHEMBL20564971 | 0.79 | EPHX2 (0.41) | HPGDUSP2SMN1; SMN2GPR119RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |