Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | OXTR | P30559 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31018063 | 0.87 | CYP19A1 (0.40) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL21783442 | 0.87 | CYP19A1 (0.40) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL29669089 | 0.86 | KDM4E (0.36) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL19614108 | 0.86 | KDM4E (0.36) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL20238565 | 0.84 | KMT2A (0.37) | KMT2AMAPK1SMN1; SMN2GAAMEN1 | |
| SCHEMBL29669086 | 0.84 | KMT2A (0.37) | KMT2AMAPK1SMN1; SMN2GAAMEN1 | |
| SCHEMBL22590218 | 0.84 | KMT2A (0.38) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL19613774 | 0.84 | KMT2A (0.38) | CYP19A1HDAC8KMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL21783397 | 0.84 | KMT2A (0.37) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA | |
| SCHEMBL31018008 | 0.84 | KMT2A (0.37) | CYP19A1KMT2AMAPK1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025096637-A1 | SUBSTITUTED ARYL SULFONAMIDES FOR USE AS SODIUM CHANNEL INHIBITORS | XENON PHARMACEUTICALS INC. (CA) | 2025-05-08 | — | — | WO | disclosed |