Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 20/20 | 0.61 |
| ▸ | PARP2 | Q9UGN5 | 8/20 | 0.59 |
| ▸ | PARP6 | Q2NL67 | 3/20 | 0.59 |
| ▸ | PARP3 | Q9Y6F1 | 3/20 | 0.59 |
| ▸ | TNKS | O95271 | 1/20 | 0.59 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31571102 | 0.98 | PARP1 (0.61) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570940 | 0.96 | PARP1 (0.66) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31571063 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570948 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570975 | 0.88 | PARP1 (0.60) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570960 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570939 | 0.88 | PARP1 (0.58) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31571096 | 0.86 | PARP1 (0.56) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570997 | 0.86 | PARP1 (0.62) | PARP1PARP2PARP6PARP3TNKS | |
| SCHEMBL31570988 | 0.86 | PARP1 (0.64) | PARP1PARP2PARP6PARP3TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025101892-A1 | POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS AND USES THEREOF | Astellas Engineered Small Molecules US, Incorporated (US) | 2025-05-15 | — | — | WO | disclosed |