Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.71 |
| ▸ | GFER | P55789 | 2/20 | 0.71 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 2/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22440000 | 1.00 | MEN1 (0.71) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL2210096 | 0.83 | MEN1 (1.00) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL20315169 | 0.81 | MEN1 (0.67) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL31572194 | 0.78 | MAPT (0.45) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL8423973 | 0.78 | MAPT (0.45) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL30969482 | 0.78 | MAPT (0.45) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL31572208 | 0.74 | KMT2A (0.54) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL22440034 | 0.74 | KMT2A (0.54) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL25533157 | 0.73 | HPGD (0.52) | MEN1KMT2AGFERHPGDSMN1; SMN2 | |
| SCHEMBL27829670 | 0.71 | KMT2A (0.72) | MEN1KMT2AGFERHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111712246-B | Bis (hydroxymethyl) pyrrolopyrazine hybrid, preparation method and application thereof | 周美吟 | 2025-05-06 | — | — | CN | disclosed |