Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 19/20 | 0.80 |
| ▸ | JAK1 | P23458 | 2/20 | 0.77 |
| ▸ | JAK2 | O60674 | 1/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31572561 | 1.00 | TYK2 (0.80) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572544 | 0.92 | TYK2 (0.79) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572593 | 0.91 | TYK2 (0.77) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572599 | 0.91 | TYK2 (0.79) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572583 | 0.90 | TYK2 (0.78) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572545 | 0.89 | TYK2 (0.83) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20688736 | 0.89 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL21726443 | 0.89 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL20688577 | 0.89 | TYK2 (1.00) | TYK2JAK1JAK2CYP3A4CYP2C19 | |
| SCHEMBL31572527 | 0.88 | TYK2 (0.79) | TYK2JAK1JAK2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119954831-A | Pyrimidopyrazoles, preparation method and medical application thereof | 江苏恒瑞医药股份有限公司 | 2025-05-09 | — | — | CN | disclosed |