SCHEMBL31574491

SCHEMBL31574491

COc1cc(/C=C/C(=O)c2ccc(Cl)cc2)ccc1F

nearest known ligand 0.76

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CXCL12 P48061 7/20 0.76
CXCR4 P61073 1/20 0.76
ABCG2 Q9UNQ0 3/20 0.68
MEN1 O00255 1/20 0.68
KMT2A Q03164 1/20 0.68
KDR P35968 1/20 0.66
MAOB P27338 2/20 0.64
MAOA P21397 1/20 0.64
TNFRSF1A P19438 1/20 0.61
ALDH1A1 P00352 1/20 0.60
KRAS P01116 1/20 0.60
ATM Q13315 1/20 0.60
SMN1; SMN2 Q16637 1/20 0.60
L3MBTL1 Q9Y468 1/20 0.60
CA1 P00915 1/20 0.60
CA2 P00918 1/20 0.60
AR P10275 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30837223 1.00 CXCL12 (0.76) CXCL12CXCR4ABCG2MEN1KMT2A
SCHEMBL13613545 0.89 ABCG2 (0.86) CXCL12CXCR4ABCG2MEN1KMT2A
SCHEMBL19183376 0.89 ABCG2 (0.86) CXCL12CXCR4ABCG2MEN1KMT2A
SCHEMBL25194287 0.86 CXCL12 (1.00) CXCL12CXCR4AR
SCHEMBL30837249 0.86 CXCL12 (1.00) CXCL12CXCR4AR
SCHEMBL25197185 0.86 CXCL12 (1.00) CXCL12CXCR4AR
SCHEMBL12662991 0.86 CXCL12 (1.00) CXCL12CXCR4AR
Water SCHEMBL30383072 0.85 CXCL12 (0.97) CXCL12CXCR4AR
SCHEMBL19782366 0.84 CXCL12 (0.73) CXCL12CXCR4ABCG2MEN1KMT2A
SCHEMBL31233046 0.84 CXCL12 (0.73) CXCL12CXCR4ABCG2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed