Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ2 | O43526 | 7/20 | 0.50 |
| ▸ | KCNQ3 | O43525 | 6/20 | 0.50 |
| ▸ | KCNQ4 | P56696 | 2/20 | 0.50 |
| ▸ | KCNQ5 | Q9NR82 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PPM1D | O15297 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22299149 | 1.00 | KCNQ2 (0.50) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL22299157 | 0.88 | KCNQ2 (0.63) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL31576851 | 0.88 | KCNQ2 (0.63) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL22299156 | 0.85 | NPC1 (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL31576979 | 0.85 | NPC1 (0.51) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL22299226 | 0.83 | KCNQ2 (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5HDAC3 | |
| SCHEMBL31577089 | 0.83 | KCNQ2 (0.53) | KCNQ2KCNQ3KCNQ4KCNQ5HDAC3 | |
| SCHEMBL22298751 | 0.82 | KCNQ2 (0.65) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL31577151 | 0.82 | KCNQ2 (0.65) | KCNQ2KCNQ3KCNQ4KCNQ5NPC1 | |
| SCHEMBL22299151 | 0.82 | KDM4E (0.59) | NPC1RAB9AALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | claimed |
| EP-3917907-B1 | MODULATORS OF POTASSIUM ION CHANNELS AND USES THEREOF | UNIV DEGLI STUDI DI SALERNO (IT) | 2025-05-21 | — | — | EP | disclosed |