Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Kaempferol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.97 |
| ▸ | MEN1 | O00255 | 9/20 | 0.97 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.97 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.97 |
| ▸ | ABCB1 | P08183 | 7/20 | 0.97 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.97 |
| ▸ | CYP1A1 | P04798 | 7/20 | 0.97 |
| ▸ | CYP1B1 | Q16678 | 7/20 | 0.97 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.97 |
| ▸ | FTO | Q9C0B1 | 6/20 | 0.97 |
| ▸ | XDH | P47989 | 6/20 | 0.97 |
| ▸ | MAPT | P10636 | 6/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.97 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.97 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.97 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.97 |
| ▸ | APP | P05067 | 5/20 | 0.97 |
| ▸ | TP53 | P04637 | 5/20 | 0.97 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.97 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Kaempferol SCHEMBL18817 | 0.98 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL1259228 | 0.98 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL29378805 | 0.98 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL30655455 | 0.98 | MEN1 (1.00) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL34461912 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL17237761 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL38651062 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL31256029 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL31749037 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 | |
| Kaempferol SCHEMBL30544809 | 0.97 | MEN1 (0.97) | MEN1KMT2ACYP1A2CYP3A4ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250161217-A1 | RADIOPROTECTIVE COMPOSITIONS AND METHODS FOR PREPARATION THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-05-22 | — | — | US | disclosed |
| US-20250161217-A1 | RADIOPROTECTIVE COMPOSITIONS AND METHODS FOR PREPARATION THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-05-22 | — | — | US | disclosed |