Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 5/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | TNKS | O95271 | 3/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 3/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 2/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31578988 | 0.92 | KIT (0.42) | KITHDAC2HDAC1PARP1MAP4K4 | |
| SCHEMBL31578981 | 0.87 | KIT (0.44) | KITHDAC2HDAC1PARP1MAP4K4 | |
| SCHEMBL30406325 | 0.84 | KIT (0.41) | KITHDAC2HDAC1PARP1GPR119 | |
| SCHEMBL31578990 | 0.83 | MAP4K4 (0.42) | KITHDAC2HDAC1PARP1MAP4K4 | |
| SCHEMBL25422069 | 0.81 | HTT (0.49) | KITHDAC2HDAC1MAP4K4GPR119 | |
| SCHEMBL30405762 | 0.81 | HTT (0.49) | KITHDAC2HDAC1MAP4K4GPR119 | |
| SCHEMBL30405719 | 0.80 | MAPK7 (0.47) | KITHDAC2HDAC1MAP4K4GPR119 | |
| SCHEMBL25232266 | 0.80 | MAPK7 (0.47) | KITHDAC2HDAC1MAP4K4GPR119 | |
| SCHEMBL25280892 | 0.79 | KIT (0.44) | KITHDAC2HDAC1PARP1MAP4K4 | |
| SCHEMBL30405237 | 0.79 | KIT (0.44) | KITHDAC2HDAC1PARP1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250163061-A1 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. | 2025-05-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250163061-A1 | INHIBITORS OF MENIN-MLL INTERACTION | MLLT1, MEN1, BMI1 | KIT 1067/4885HDAC2 241/4885HDAC1 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.