Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.43 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 2/20 | 0.42 |
| ▸ | JAK3 | P52333 | 2/20 | 0.42 |
| ▸ | ATR | Q13535 | 3/20 | 0.41 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31580423 | 1.00 | PDK2 (0.45) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580715 | 1.00 | PDK2 (0.45) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580870 | 0.94 | PDK2 (0.44) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580594 | 0.94 | PDK2 (0.44) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580792 | 0.94 | PDK2 (0.44) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580673 | 0.93 | PDE4B (0.46) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580758 | 0.93 | PDE4B (0.46) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580755 | 0.93 | PDE4B (0.46) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580723 | 0.88 | PDE4B (0.46) | PDK2PDE4BKDM1ATLR9TLR8 | |
| SCHEMBL31580862 | 0.88 | PDK2 (0.45) | PDK2KDM1ATLR9TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | claimed |
| WO-2025106722-A1 | INHIBITORS OF STK33, RET, CLK, AND/OR RELATED KINASES AND METHODS USING SAME | BAYLOR COLLEGE OF MEDICINE (US) | 2025-05-22 | — | — | WO | disclosed |