Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 8/20 | 0.67 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.60 |
| ▸ | ELOVL1 | Q9BW60 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3184587 | 1.00 | HDAC4 (0.67) | HDAC4AKR1C1ELOVL1MAPTTHRB | |
| SCHEMBL2867660 | 0.98 | HDAC4 (0.65) | HDAC4AKR1C1ELOVL1MAPTTHRB | |
| SCHEMBL29567033 | 0.98 | HDAC4 (0.65) | HDAC4AKR1C1ELOVL1MAPTTHRB | |
| SCHEMBL5637311 | 0.96 | HDAC4 (0.62) | HDAC4AKR1C1ELOVL1MAPTTHRB | |
| SCHEMBL30501854 | 0.96 | HDAC4 (0.62) | HDAC4AKR1C1ELOVL1MAPTTHRB | |
| SCHEMBL31125559 | 0.94 | HDAC4 (0.59) | HDAC4AKR1C1ELOVL1 | |
| SCHEMBL301133 | 0.94 | HDAC4 (0.59) | HDAC4AKR1C1ELOVL1 | |
| SCHEMBL1627778 | 0.86 | HDAC4 (0.51) | HDAC4AKR1C1ELOVL1MAPTALDH1A1 | |
| SCHEMBL31382198 | 0.86 | HDAC4 (0.51) | HDAC4AKR1C1ELOVL1 | |
| SCHEMBL5766858 | 0.86 | HDAC4 (0.51) | HDAC4AKR1C1ELOVL1MAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104079-A1 | SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2025-05-22 | — | — | WO | disclosed |