SCHEMBL31581178

SCHEMBL31581178

CCCCc1nc2c(N)nc3cc(C(=O)OC)ccc3c2n1Cc1ccc(CNC(=O)OC(C)(C)C)cc1

nearest known ligand 0.76

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 17/20 0.76
▸ TLR8 Q9NR97 11/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30870446 0.91 TLR7 (0.63) TLR7TLR8
SCHEMBL29947776 0.88 TLR7 (0.82) TLR7TLR8
SCHEMBL15698491 0.88 TLR7 (0.82) TLR7TLR8
SCHEMBL30870451 0.87 TLR7 (0.81) TLR7TLR8
SCHEMBL19196883 0.86 TLR7 (0.87) TLR7TLR8
SCHEMBL19196887 0.86 TLR7 (0.87) TLR7TLR8
SCHEMBL19196890 0.86 TLR7 (1.00) TLR7TLR8
SCHEMBL30870435 0.86 TLR7 (0.62) TLR7TLR8
SCHEMBL31581270 0.86 TLR7 (0.55) TLR7TLR8
SCHEMBL13837167 0.86 TLR7 (0.69) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103490-A1 N-OXIDE IMMUNE AGONISTS ACTIVATION BY RADIOTHERAPY Beijing Changping Laboratory (CN) 2025-05-22 — — WO disclosed
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