SCHEMBL3158255

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3159151	0.98	CYP1A2 (0.52)	CYP1A2CYP2A6CYP17A1CYP11B1CYP21A2
	SCHEMBL3166607	0.89	CYP1A2 (0.53)	CYP1A2CYP2A6CYP17A1PGRTAAR1
	SCHEMBL3157962	0.89	CYP1A2 (0.53)	CYP1A2CYP2A6CYP17A1PGRTAAR1
	SCHEMBL3257252	0.89	CYP1A2 (0.43)	CYP1A2CYP2A6CYP17A1CYP11B1CYP21A2
	SCHEMBL3158271	0.86	TAAR1 (0.59)	CYP1A2CYP2A6CYP17A1CYP11B1TAAR1
	SCHEMBL3153225	0.86	CYP17A1 (0.45)	CYP17A1CYP11B1CYP21A2PGRTAAR1
	SCHEMBL3257876	0.85	CYP1A2 (0.43)	CYP1A2CYP2A6CYP17A1CYP11B1CYP21A2
	SCHEMBL13282199	0.85	CYP17A1 (0.47)	CYP17A1CYP11B1CYP21A2TAAR1CYP3A4
	SCHEMBL3173709	0.84	CYP1A2 (0.48)	CYP1A2CYP2A6CYP17A1CYP11B1HRH3
	SCHEMBL3163338	0.84	TAAR1 (0.56)	CYP1A2CYP2A6CYP17A1CYP11B1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.