SCHEMBL31585504

SCHEMBL31585504

O=C1CCC(c2ccc(CC3CCNCC3)cc2)C(=O)N1

nearest known ligand 0.56

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 15/20 0.56
▸ DDB1 Q16531 14/20 0.56
▸ POLB P06746 1/20 0.49
▸ GBA1 P04062 1/20 0.47
▸ GSPT1 P15170 1/20 0.43
▸ HTT P42858 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26641368 0.86 CRBN (0.54) CRBNDDB1POLBGSPT1
SCHEMBL25187957 0.81 CRBN (0.64) CRBNDDB1POLB
SCHEMBL24125814 0.81 CRBN (0.64) CRBNDDB1POLB
SCHEMBL30726422 0.80 CRBN (0.64) CRBNDDB1POLB
SCHEMBL31382199 0.80 CRBN (0.64) CRBNDDB1POLB
SCHEMBL27039435 0.80 CRBN (0.52) CRBNDDB1POLBGSPT1
Hydrochloric Acid SCHEMBL23301197 0.80 CRBN (0.62) CRBNDDB1POLB
SCHEMBL26641290 0.79 CRBN (0.66) CRBNDDB1POLBGSPT1
Hydrochloric Acid SCHEMBL31232781 0.79 CRBN (0.51) CRBNDDB1POLBGSPT1
SCHEMBL25217869 0.78 CRBN (0.64) CRBNDDB1POLBGSPT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025106482-A1 COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-05-22 — — WO disclosed
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