SCHEMBL31586873

SCHEMBL31586873

O=C1CCC(N2C(=O)c3cc(F)c(N4CCC(CCCCO)CC4)cc3C2=O)C(=O)N1

nearest known ligand 0.66

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 18/20 0.66
▸ DDB1 Q16531 11/20 0.49
▸ IKZF3 Q9UKT9 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.45
▸ CHRM2 P08172 1/20 0.45
▸ OPRM1 P35372 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ TSHR P16473 1/20 0.45
▸ TDP1 Q9NUW8 1/20 0.45
▸ AR P10275 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31585976 0.97 CRBN (0.67) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29877703 0.93 CRBN (0.69) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29094603 0.93 CRBN (0.69) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL22565579 0.89 CRBN (0.72) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL29877735 0.88 CRBN (0.62) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31586203 0.88 CRBN (0.62) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL25246277 0.86 CRBN (0.66) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31306490 0.85 CRBN (0.67) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL31587067 0.85 CRBN (0.73) CRBNDDB1IKZF3ALDH1A1CHRM2
SCHEMBL20046347 0.85 CRBN (0.66) CRBNDDB1IKZF3ALDH1A1CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025103502-A1 COMPOUNDS AND METHODS OF TREATING CANCERS CULLGEN INC. (US) 2025-05-22 — — WO disclosed
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