Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 10/20 | 0.39 |
| ▸ | CDK2 | P24941 | 10/20 | 0.39 |
| ▸ | GSK3B | P49841 | 4/20 | 0.38 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 4/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.35 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.35 |
| ▸ | KDM4A | O75164 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31587008 | 0.90 | CDK2 (0.38) | CCNE1CDK2GSK3BCRACR2AKDM5A | |
| SCHEMBL31587024 | 0.88 | CRACR2A (0.44) | CCNE1CDK2GSK3BCRACR2AKDM5A | |
| SCHEMBL31586967 | 0.85 | KCNJ6 (0.41) | CCNE1CDK2CRACR2AAR | |
| SCHEMBL31587183 | 0.84 | CDK2 (0.53) | CCNE1CDK2GSK3B | |
| SCHEMBL31587153 | 0.83 | CDK2 (0.36) | CCNE1CDK2GSK3BCRACR2AAR | |
| SCHEMBL31587062 | 0.83 | CDK2 (0.37) | CCNE1CDK2GSK3BCRACR2AAR | |
| SCHEMBL31587991 | 0.81 | CRACR2A (0.38) | CCNE1CDK2GSK3BCRACR2AAR | |
| SCHEMBL31586737 | 0.81 | AR (0.35) | CCNE1CDK2GSK3BCRACR2AAR | |
| SCHEMBL31588043 | 0.80 | AR (0.35) | CCNE1CDK2GSK3BCRACR2AAR | |
| SCHEMBL31587271 | 0.80 | AR (0.49) | ARCACNA1GCACNA1HCACNA1I |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | claimed |
| WO-2025104236-A1 | PYRAZOLE COMPOUNDS AS CULLIN RING UBIQUITIN LIGASE COMPOUNDS | PROXYGEN GMBH (AT) | 2025-05-22 | — | — | WO | disclosed |