Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.49 |
| ▸ | CA1 | P00915 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.49 |
| ▸ | CA7 | P43166 | 2/20 | 0.49 |
| ▸ | CA9 | Q16790 | 2/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.49 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.49 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | HMGCR | P04035 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692871 | 1.00 | HTT (0.50) | HTTCA12CA1CA2CA7 | |
| SCHEMBL20802856 | 0.93 | KDM4E (0.51) | HTTCA12CA1CA2CA7 | |
| SCHEMBL30447954 | 0.87 | KDM4E (0.56) | HTTKDM4EGAALCKFYN | |
| SCHEMBL25341632 | 0.87 | KDM4E (0.56) | HTTKDM4EGAALCKFYN | |
| SCHEMBL9080835 | 0.86 | GAA (0.50) | HTTCA12CA1CA2CA7 | |
| SCHEMBL383036 | 0.85 | GAA (0.53) | HTTKDM4EGAALCKFYN | |
| SCHEMBL8980590 | 0.85 | HTT (0.68) | HTTCA12CA1CA2CA7 | |
| SCHEMBL4466238 | 0.84 | HTT (0.72) | HTTKDM4EGAAHMGCRLCK | |
| SCHEMBL15074288 | 0.84 | LCK (0.59) | HTTCA12CA1CA2CA7 | |
| SCHEMBL3461530 | 0.83 | KDM4E (0.57) | HTTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106974-A1 | PRODRUG MOIETIES AND COMPOUNDS COMPRISING THE SAME | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2025-05-22 | — | — | WO | disclosed |