Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WRN | Q14191 | 1/20 | 0.54 |
| ▸ | NOD2 | Q9HC29 | 3/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25035182 | 0.89 | WRN (0.61) | WRNNOD2NOD1NPC1MAPT | |
| SCHEMBL30038140 | 0.86 | WRN (0.58) | WRNNOD2NOD1NPC1MAPT | |
| SCHEMBL30038998 | 0.86 | WRN (0.58) | WRNNOD2NOD1NPC1MAPT | |
| SCHEMBL25037086 | 0.86 | WRN (0.65) | WRNNOD2NOD1MAPTALDH1A1 | |
| SCHEMBL30038334 | 0.86 | WRN (0.65) | WRNNOD2NOD1MAPTALDH1A1 | |
| SCHEMBL25035229 | 0.85 | WRN (0.51) | WRNALDH1A1SMN1; SMN2PIK3CAUSP2 | |
| SCHEMBL25037372 | 0.85 | WRN (0.51) | WRNMAPTALDH1A1ESR2PIK3CA | |
| Trifluoroacetic Acid SCHEMBL31590572 | 0.85 | WRN (0.54) | WRNNOD2NOD1MAPK1MAPT | |
| SCHEMBL25037129 | 0.85 | WRN (0.64) | WRNNOD2NOD1MAPTALDH1A1 | |
| SCHEMBL25037295 | 0.85 | WRN (0.68) | WRNNOD2NOD1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040475-A | Compounds as WRN inhibitors and uses thereof | 南京圣和药业股份有限公司 | 2025-05-27 | — | — | CN | disclosed |