Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALPL | P05186 | 1/20 | 0.58 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.58 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31590526 | 0.91 | SMN1; SMN2 (0.70) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590700 | 0.88 | MAPT (0.58) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590505 | 0.88 | MAPT (0.58) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590859 | 0.88 | MAPT (0.63) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31591010 | 0.88 | MAPT (0.55) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590936 | 0.86 | MAPT (0.56) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590588 | 0.85 | SMN1; SMN2 (0.55) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31590904 | 0.84 | MAPT (0.54) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31591037 | 0.84 | MAPT (0.55) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL31591054 | 0.80 | SLC2A1 (0.45) | MAPTNPSR1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120040420-A | Heterocyclic-pyrazole amine derivatives, preparation method thereof and application thereof in resisting tubercle bacillus infection | 中国医学科学院医药生物技术研究所 | 2025-05-27 | — | — | CN | disclosed |