SCHEMBL31590735

SCHEMBL31590735

CC(=O)c1cccn1Cc1ccc(I)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 9/20 0.46
CNR1 P21554 3/20 0.46
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA9 Q16790 2/20 0.46
KDM4E B2RXH2 1/20 0.46
SCN3A Q9NY46 2/20 0.42
LMNA P02545 1/20 0.41
MAP3K14 Q99558 1/20 0.41
POLB P06746 1/20 0.40
VEGFA P15692 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
EPHX2 P34913 1/20 0.39
BRD4 O60885 1/20 0.38
BRD2 P25440 1/20 0.38
BRD3 Q15059 1/20 0.38
BRDT Q58F21 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31590809 0.85 CNR2 (0.60) CNR2CNR1CA12CA1CA2
SCHEMBL31590941 0.85 CNR2 (0.47) CNR2CNR1CA12CA1CA2
SCHEMBL4674844 0.85 CA12 (0.61) CNR2CNR1CA12CA1CA2
SCHEMBL31590800 0.85 VEGFA (0.55) CNR2CNR1CA12CA1CA2
SCHEMBL5252962 0.85 CNR2 (0.55) CNR2CNR1CA12CA1CA2
SCHEMBL31590593 0.84 HDAC3 (0.48) CNR2CNR1CA12CA1CA2
SCHEMBL31590709 0.83 KMT2A (0.49) CNR2CNR1CA12CA1CA2
SCHEMBL31590889 0.81 HDAC8 (0.51) CNR2CNR1CA12CA1CA2
SCHEMBL2980287 0.80 CNR2 (0.52) CNR2CNR1CA12CA1CA2
SCHEMBL31591022 0.79 CA12 (0.49) CNR2CNR1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120040330-A Benzyl pyrrole compound and preparation method and application thereof 深圳技术大学 2025-05-27 CN disclosed