SCHEMBL31591669

SCHEMBL31591669

O=C(O)CC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(c1ccccc1)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ MDM4 O15151 2/20 0.46
▸ TP53 P04637 2/20 0.46
▸ KMT2A Q03164 1/20 0.45
▸ PTPN1 P18031 3/20 0.43
▸ CASP3 P42574 2/20 0.42
▸ TLR2 O60603 2/20 0.41
▸ MDM2 Q00987 1/20 0.41
▸ FABP7 O15540 1/20 0.40
▸ FABP5 Q01469 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29992297 0.91 KMT2A (0.51) MDM4TP53KMT2APTPN1CASP3
SCHEMBL17826038 0.91 KMT2A (0.51) MDM4TP53KMT2APTPN1CASP3
SCHEMBL31537233 0.89 MDM4 (0.46) MDM4TP53PTPN1CASP3TLR2
SCHEMBL17751704 0.87 MDM4 (0.43) MDM4TP53PTPN1CASP3TLR2
SCHEMBL26474537 0.85 MDM2 (0.46) MDM4TP53TLR2MDM2
SCHEMBL17751673 0.84 TLR2 (0.46) MDM4TP53TLR2MDM2
SCHEMBL31591662 0.84 MDM2 (0.42) MDM4TP53CASP3TLR2MDM2
SCHEMBL13049087 0.84 TLR2 (0.47) MDM4TP53KMT2ATLR2MDM2
SCHEMBL31624497 0.84 HDAC1 (0.48) KMT2ATLR2
SCHEMBL31624368 0.84 HDAC1 (0.48) KMT2ATLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF REGENERON PHARMACEUTICALS, INC. (US) 2025-05-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171516-A1 PEPTIDE ACIDS AS A GLP1R AGONIST AND ANTIBODY-DRUG CONJUGATES THEREOF GLP1R, GIPR, GCGR MDM4 4740/4885TP53 3214/4885KMT2A 1564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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