Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.34 |
| ▸ | NAMPT | P43490 | 9/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 2/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31600340 | 0.92 | MEN1 (0.34) | NAMPTMCHR1MEN1MAPTTSHR | |
| SCHEMBL31600469 | 0.91 | MCHR1 (0.36) | JAK3RETNAMPTMCHR1MTOR | |
| SCHEMBL31600156 | 0.90 | JAK3 (0.35) | JAK3RETMEN1MAPTTSHR | |
| SCHEMBL31600740 | 0.89 | JAK3 (0.35) | JAK3RETWNT3A | |
| SCHEMBL31600536 | 0.89 | JAK3 (0.35) | JAK3RETNAMPTMAPTWNT3A | |
| SCHEMBL31600336 | 0.88 | JAK3 (0.34) | JAK3RET | |
| SCHEMBL31600530 | 0.88 | JAK3 (0.34) | JAK3RETNAMPT | |
| SCHEMBL31600512 | 0.88 | MEN1 (0.43) | NAMPTMCHR1MEN1MAPTTSHR | |
| SCHEMBL31600523 | 0.86 | JAK3 (0.35) | JAK3RETWNT3A | |
| SCHEMBL31600195 | 0.86 | JAK3 (0.35) | JAK3RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |