Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31600954 | 0.87 | STK17B (0.46) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL31600842 | 0.76 | NQO2 (0.42) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL31599943 | 0.75 | STK17B (0.46) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL31600169 | 0.74 | NQO2 (0.41) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL18072351 | 0.73 | CACNA1H (0.46) | GAASTK17BSTK17ACACNA1HCACNA1B | |
| SCHEMBL4864493 | 0.73 | NQO2 (0.40) | NQO2STK17BSTK17AALDH1A1HTT | |
| SCHEMBL20399840 | 0.72 | CACNA1H (0.45) | LMNAGAASTK17BSTK17AKDM4E | |
| SCHEMBL23979680 | 0.72 | HTT (0.51) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL3629297 | 0.70 | NQO2 (0.48) | LMNAHPGDGAANQO2STK17B | |
| SCHEMBL1186965 | 0.70 | CACNA1H (0.45) | GAANQO2STK17BSTK17AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111547-A1 | 2,3-DIHYDROPYROLLOPYRIDINE CARBOXAMIDE COMPOUNDS AND METHODS OF USE THEREOF | RGENTA THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |