SCHEMBL31601583

SCHEMBL31601583

O=C1CCC(N2Cc3c(NCCCl)cccc3C2=O)C(=O)N1

nearest known ligand 0.64

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 12/20 0.64
▸ IKZF3 Q9UKT9 6/20 0.62
▸ DDB1 Q16531 3/20 0.62
▸ IKZF1 Q13422 3/20 0.62
▸ TNF P01375 3/20 0.62
▸ IL1B P01584 3/20 0.62
▸ BRD4 O60885 2/20 0.62
▸ MAP1LC3B Q9GZQ8 4/20 0.59
▸ STAT3 P40763 1/20 0.55
▸ CSNK1A1 P48729 1/20 0.53
▸ IKZF2 Q9UKS7 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21907827 1.00 CRBN (0.64) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL19453060 0.93 CRBN (0.60) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL17536570 0.91 CRBN (0.66) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL24818144 0.90 CRBN (0.65) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL29822441 0.90 CRBN (0.65) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL17536572 0.89 CRBN (0.67) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL21602681 0.89 CRBN (0.64) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL17536561 0.89 CRBN (0.64) CRBNIKZF3DDB1IKZF1TNF
SCHEMBL23093113 0.89 CRBN (0.65) CRBNIKZF3DDB1IKZF1TNF
Hydrochloric Acid SCHEMBL31554721 0.88 CRBN (0.64) CRBNIKZF3DDB1IKZF1TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025108411-A1 EP300/CBP REGULATOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF 北京沐华生物科技有限责任公司 2025-05-30 — — WO disclosed
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