SCHEMBL31603669

SCHEMBL31603669

[2H]C([2H])(c1cnn(C)c1)N1C(=O)c2cc(S(=O)(=O)NC3(C)CC3)ccc2N2C1=NCC2C

nearest known ligand 0.49

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ PARG Q86W56 20/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26689060 1.00 PARG (0.49) PARG
SCHEMBL30643955 1.00 PARG (0.49) PARG
SCHEMBL26688633 0.92 PARG (0.57) PARG
SCHEMBL31605774 0.90 PARG (0.49) PARG
SCHEMBL31605784 0.90 PARG (0.41) PARG
SCHEMBL31605836 0.89 PARG (0.47) PARG
SCHEMBL31605823 0.89 PARG (0.47) PARG
SCHEMBL31605803 0.89 PARG (0.47) PARG
SCHEMBL31605839 0.89 PARG (0.47) PARG
SCHEMBL26688948 0.89 PARG (0.49) PARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025111339-A1 TREATMENT OF CANCER WITH A PARG INHIBITOR 858 THERAPEUTICS, INC. (US) 2025-05-30 — — WO claimed
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