Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 11/20 | 0.59 |
| ▸ | MEN1 | O00255 | 10/20 | 0.59 |
| ▸ | NPC1 | O15118 | 7/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | XBP1 | P17861 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3160505 | 1.00 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL17620472 | 0.86 | MEN1 (0.65) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3171261 | 0.81 | MEN1 (0.56) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3171258 | 0.81 | MEN1 (0.56) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3259941 | 0.81 | MEN1 (0.58) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3164901 | 0.80 | MEN1 (0.57) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3152969 | 0.80 | MEN1 (0.57) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3261694 | 0.80 | MEN1 (0.57) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3157054 | 0.80 | MEN1 (0.57) | KMT2AMEN1NPC1RAB9ANR2F2 | |
| SCHEMBL3157063 | 0.80 | MEN1 (0.57) | KMT2AMEN1NPC1RAB9ANR2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756110-B1 | 7H-PYRROLO[2,3-d]PYRIMIDINE DERIVATIVES, AS WELL AS THEIR THERAPEUTICALLY ACCEPTABLE SALTS, PHARMACEUTICAL PREPARATIONS CONTAINING THEM AND PROCESS FOR PRODUCTION THE ACTIVE AGENT | SZOLCSANYI JANOS (HU) | 2010-03-31 | — | — | EP | disclosed |