Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.63 |
| ▸ | CRBN | Q96SW2 | 13/20 | 0.53 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 2/20 | 0.39 |
| ▸ | RAF1 | P04049 | 2/20 | 0.39 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.39 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.38 |
| ▸ | PLK4 | O00444 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605498 | 1.00 | AR (0.63) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL31605536 | 1.00 | AR (0.63) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL20046199 | 0.94 | AR (0.57) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL31605511 | 0.91 | AR (0.65) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL31605518 | 0.91 | AR (0.65) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL31258560 | 0.90 | AR (0.64) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL30488998 | 0.89 | CRBN (0.54) | ARCRBNDDB1BTKRAF1 | |
| SCHEMBL29058484 | 0.89 | CRBN (0.54) | ARCRBNDDB1BTKRAF1 | |
| SCHEMBL20046406 | 0.86 | CRBN (0.56) | ARCRBNDDB1IKZF3BTK | |
| SCHEMBL29058510 | 0.85 | CRBN (0.50) | ARCRBNDDB1BTKRAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025108404-A1 | HETEROCYCLIC COMPOUND OF BIFUNCTIONAL CHIMERA FOR TARGETED DEGRADATION OF ANDROGEN RECEPTOR AND USE THEREOF | 广东东阳光药业股份有限公司 | 2025-05-30 | — | — | WO | disclosed |