Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 20/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31605860 | 0.93 | PARG (0.51) | PARG | |
| SCHEMBL31605836 | 0.91 | PARG (0.47) | PARG | |
| SCHEMBL31605839 | 0.91 | PARG (0.47) | PARG | |
| SCHEMBL31605803 | 0.91 | PARG (0.47) | PARG | |
| SCHEMBL31605823 | 0.91 | PARG (0.47) | PARG | |
| SCHEMBL31605826 | 0.91 | PARG (0.43) | PARG | |
| SCHEMBL31605802 | 0.91 | PARG (0.43) | PARG | |
| SCHEMBL31605889 | 0.91 | PARG (0.43) | PARG | |
| SCHEMBL31605867 | 0.90 | PARG (0.43) | PARG | |
| SCHEMBL31605893 | 0.90 | PARG (0.44) | PARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025111492-A1 | INHIBITORS OF PARG | 858 THERAPEUTICS, INC. (US) | 2025-05-30 | — | — | WO | disclosed |