Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.30 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3176236 | 0.87 | TSHR (0.39) | TSHRALDH1A1TDP1 | |
| SCHEMBL3176193 | 0.86 | TDP1 (0.35) | TSHRLMNATDP1 | |
| SCHEMBL3161143 | 0.85 | TSHR (0.34) | TSHR | |
| SCHEMBL3170799 | 0.85 | TSHR (0.40) | TSHRTDP1 | |
| SCHEMBL3177444 | 0.83 | TSHR (0.37) | TSHRTDP1 | |
| SCHEMBL3168263 | 0.83 | TSHR (0.33) | TSHR | |
| SCHEMBL3170526 | 0.82 | TSHR (0.44) | TSHRALDH1A1 | |
| SCHEMBL10537484 | 0.81 | TSHR (0.37) | TSHRALDH1A1LMNATDP1MAPT | |
| SCHEMBL3177360 | 0.81 | TSHR (0.35) | TSHRTDP1 | |
| SCHEMBL9633230 | 0.81 | MGAM (0.37) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645607-B2 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-12 | — | — | US | disclosed |
| EP-1705252-B1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL CO (JP) | 2008-07-16 | — | — | EP | disclosed |
| US-20060216806-A1 | Method for producing optically active N-protected-propargylglycine | SUMITOMO CHEMICAL COMPANY, LIMITED | 2006-09-28 | — | — | US | disclosed |
| EP-1705252-A1 | Method for producing optically active N-protected-propargylglycine | Sumitomo Chemical Company, Limited (JP) | 2006-09-27 | — | — | EP | disclosed |