Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PREP | P48147 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27044706 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30863032 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30220278 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL27044708 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL31534303 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30680871 | 1.00 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL27044698 | 0.88 | CHRM2 (0.38) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL24985590 | 0.86 | DDB1 (0.36) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30156657 | 0.86 | DDB1 (0.36) | CHRM2CHRM1CHRM3DDB1CRBN | |
| SCHEMBL30449044 | 0.86 | DDB1 (0.36) | CHRM2CHRM1CHRM3DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4640689-A1 | CRYSTAL FORM OF KRAS G12D INHIBITOR AND PREPARATION METHOD THEREFOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-10-29 | — | — | EP | disclosed |
| EP-4563151-A1 | PHARMACEUTICAL COMPOSITION COMPRISING KRAS G12D INHIBITOR | Jiangsu Hengrui Pharmaceuticals Co., Ltd. (CN) | 2025-06-04 | — | — | EP | disclosed |