Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 5/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 5/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.37 |
| ▸ | GABRE | P78334 | 1/20 | 0.37 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.37 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31612887 | 1.00 | JAK1 (0.38) | JAK1TLR7TNFGRM5GRM1 | |
| SCHEMBL31282023 | 0.86 | TNF (0.39) | JAK1TNFGRM5GRM1PDK4 | |
| SCHEMBL31612864 | 0.85 | HTT (0.42) | TLR7 | |
| SCHEMBL31620111 | 0.85 | HTT (0.42) | TLR7 | |
| SCHEMBL31134648 | 0.81 | MAPT (0.44) | — | |
| SCHEMBL31282073 | 0.78 | PDK4 (0.38) | JAK1GRM5GRM1PDK4GABRP | |
| SCHEMBL31134476 | 0.77 | MAPT (0.41) | — | |
| SCHEMBL31701176 | 0.77 | BRD4 (0.39) | TLR7GRM5GRM1PDK4SCN9A | |
| SCHEMBL31612878 | 0.77 | PDE1B (0.40) | — | |
| SCHEMBL31639698 | 0.76 | PDK4 (0.42) | TLR7GRM5GRM1PDK4HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119380-A1 | ESTROGEN RECEPTOR MODULATOR AND USE THEREOF | 江苏威凯尔医药科技股份有限公司 | 2025-06-12 | — | — | WO | disclosed |