SCHEMBL31624428

SCHEMBL31624428

CC(C)(C)OC(=O)[C@H](CCC(=O)NCCOCCOCC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)O)NC(=O)CCCCCCCCCCCCCCCCP(=O)(OC(C)(C)C)OC(C)(C)C

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.49
▸ SIRT2 Q8IXJ6 5/20 0.47
▸ SIRT1 Q96EB6 2/20 0.47
▸ FOLH1 Q04609 2/20 0.43
▸ SIRT3 Q9NTG7 1/20 0.43
▸ KLK7 P49862 1/20 0.41
▸ KLK5 Q9Y337 1/20 0.41
▸ TGM2 P21980 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31624457 1.00 GLP1R (0.49) GLP1RSIRT2SIRT1FOLH1SIRT3
SCHEMBL31624398 1.00 GLP1R (0.49) GLP1RSIRT2SIRT1FOLH1SIRT3
SCHEMBL31624472 1.00 GLP1R (0.49) GLP1RSIRT2SIRT1FOLH1SIRT3
SCHEMBL31624459 1.00 GLP1R (0.49) GLP1RSIRT2SIRT1FOLH1SIRT3
SCHEMBL31631358 0.91 GLP1R (0.53) GLP1RSIRT2SIRT1FOLH1SIRT3
SCHEMBL31624510 0.90 SIRT2 (0.42) GLP1RSIRT2SIRT1SIRT3KLK7
SCHEMBL31624416 0.90 SIRT2 (0.42) GLP1RSIRT2SIRT1SIRT3KLK7
SCHEMBL31624450 0.90 SIRT2 (0.42) GLP1RSIRT2SIRT1SIRT3KLK7
SCHEMBL31624501 0.89 SIRT2 (0.54) SIRT2SIRT1FOLH1SIRT3KLK7
SCHEMBL31624426 0.89 SIRT2 (0.54) SIRT2SIRT1FOLH1SIRT3KLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
WO-2025128624-A2 HYBRID PEPTIDE COMPOUNDS HAVING A SUBSTITUTED TRYPTOPHAN RESIDUE OR A TERMINAL SUBSTITUENT CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
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