SCHEMBL31624487

SCHEMBL31624487

CC(C)(C)OC(=O)N[C@@H](CCCCNC(=O)CC[C@H](NC(=O)CCCCCCCCCCCCCCCCCCP(=O)(OC(C)(C)C)OC(C)(C)C)C(=O)OC(C)(C)C)C(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)OC(c1ccccc1)(c1ccccc1)c1ccccc1Cl

nearest known ligand 0.49

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ SIRT2 Q8IXJ6 10/20 0.49
▸ SIRT1 Q96EB6 8/20 0.42
▸ SIRT3 Q9NTG7 8/20 0.42
▸ KLK7 P49862 2/20 0.42
▸ KLK5 Q9Y337 2/20 0.42
▸ TPSAB1 Q15661 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31624430 1.00 SIRT2 (0.49) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31631370 0.92 SIRT2 (0.52) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31631382 0.92 SIRT2 (0.52) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624450 0.91 SIRT2 (0.42) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624416 0.91 SIRT2 (0.42) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624589 0.91 SIRT2 (0.42) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624510 0.91 SIRT2 (0.42) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624501 0.90 SIRT2 (0.54) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624426 0.90 SIRT2 (0.54) SIRT2SIRT1SIRT3KLK7KLK5
SCHEMBL31624601 0.87 SIRT2 (0.49) SIRT2SIRT1SIRT3KLK7KLK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025128626-A1 HYBRID PEPTIDE COMPOUNDS HAVING A MODIFIED LYSINE RESIDUE CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
WO-2025128624-A2 HYBRID PEPTIDE COMPOUNDS HAVING A SUBSTITUTED TRYPTOPHAN RESIDUE OR A TERMINAL SUBSTITUENT CARMOT THERAPEUTICS, INC. (US) 2025-06-19 — — WO disclosed
Send feedback